Researchers have studied how sebaceous glands develop and are maintained in the skin and how cancer mutations affect the behaviour of stem cells. Surprisingly, they found that these mutations do not cause cells to divide more often as expected, but instead cause stem cells to generate more stem cells and not mature sebaceous gland cells when they divide.
The researchers responsible for this study are from the Biotech Research & Innovation Centre (BRIC) and the Novo Nordisk Foundation Center for Stem Cell Biology (DanStem) at the University of Copenhagen, the University of Cambridge and the Université Cote d’Azur in Nice. The French members of the team are: Soline Estrach, Sabrina Pisano and Chloe Feral. The research is detailed in Nature Cell Biology.
Read the research paper: Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states. Marianne Stemann Andersen et al. Nature Cell Biology 10.1038/s41556-019-0362-x.