Researchers from the University of Bristol in the UK and the French National Centre for Scientific Research (CNRS) in Grenoble, together with Oracle have teamed up to find a way to make vaccines that are thermostable and can be designed quickly. They have developed a new type of vaccine for the mosquito-borne virus Chikungunya that can be stored at warmer temperatures, removing the need for refrigeration. The technique makes use of a synthetic protein scaffold that could revolutionise the way vaccines are designed, produced and stored. The work is reported in Science Advances.
Read the research paper: Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically-encoded multi-epitope display. Vragniau et al. Science Advances 10.1126/sciadv.aaw2853