Hello LABNAUT readers,
Today we learn about targeting senescent cells without eliminating them to live longer in good health, developing greener and sustainable energy with hydrogen and how melting ice will aggravate climate change.
Eliminating senescent liver cells in mice aggravates the deterioration of liver functions
Eliminating the senescent cells that accumulate in the body is touted as a promising anti-aging therapeutic strategy. New experiments by Dmitry Bulavin at the Institut de Recherche sur le Cancer et le Veillissement (Inserm/CNRS/University Côte d’Azur) and his colleagues are now casting doubt on this approach. The researchers have shown that, in mice, eliminating these senescent liver cells aggravated the deterioration of liver functions even more than aging itself. Their results are published in Cell Metabolism.
Reference: Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan. Laurent Grosse, Nicole Wagner, Alexander Emelyanov, Clement Molina, Sandra Lacas-Gervais, Kay Dietrich Wagner, Dmitry V. Bulavin. Cell Metabolism
Getting more environmentally friendly electric power from chemical energy?
Together with industrial partners, scientists from Bordeaux are developing several projects on producing and using hydrogen for new technological solutions in the energy sector.
« Getting more environmentally friendly electric power from chemical energy? This is entirely feasible with hydrogen, oxygen and a fuel cell, » explains Fabrice Mauvy, professor of solid-state chemistry and electrochemistry at IUT de Bordeaux at the Institut de chimie de la matière condensée de Bordeaux (ICMCB – CNRS, Bordeaux INP/Université de Bordeaux). Non-polluting, the principle of the fuel cell, or hydrogen cell, is based on a simple reaction: hydrogen + oxygen → electricity + water. »
Melting ice aggravates climate change
The so-called Köppen classification is based on global precipitation and temperature to define five climate zones, from tropical to polar. A team of researchers, mainly from the UMR Espace-Dev, have now included different scenarios of accelerated melting of the ice caps in Greenland and Antarctica in this classification to determine how they will impact future climate change.
The results are incontestable: « The consequences would occur as early as 2050 and would be greater than those predicted by the RCP8.5 climate scenario, which is the most pessimistic scenario developed by the IPCC, » explains Dimitri Defrance, the first author of the study. « If Antarctica melted first, rainfall would increase in West Africa and the climate would become drier in Australia. If it were Greenland first, on the other hand, the size of the Sahel desert area would double and it would rain more in Latin America and Australia. Its impact on climate change would also be greater. »
Reference: Dimitri Defrance, Thibault Catry, Amélie Rajaud, Nadine Dessay, Benjamin Sultan. Impacts of Greenland and Antarctic Ice Sheet melt on future Köppen climate zone changes simulated by an atmospheric and oceanic general circulation model. Applied Geography
QUOTE OF THE DAY:
« At this important juncture, our research must be at the service of public policy. We must be available for that. » Tanguy Bernard, Department Head, GREThA (UMR 5113 UB-CNRS)