healthmedicineresearch news

E. coli gain a foothold by changing their diets in inflammatory bowel disease

By 6th November 2019 November 28th, 2019 No Comments

In a new paper in Nature Microbiology, researchers at Michigan Medicine tgether with colleagues at Insem describe how bad bacteria gain a foothold over good bacteria in irritable bowel syndrome (IBD)  and how something as simple as a diet change might reverse it. “The same bacteria are present in healthy and inflamed digestive tracts,” says Nobuhiko Kamada, of the division of gastroenterology in the Department of Internal Medicine at Michigan. “They just change their competition.”

Read the research paper: Sho Kitamoto, Christopher J. Alteri, Michael Rodrigues, Hiroko Nagao-Kitamoto, Kohei Sugihara, Stephanie D. Himpsl, Malak Bazzi, Mao Miyoshi, Tatsuki Nishioka, Atsushi Hayashi, Tina L. Morhardt, Peter Kuffa, Helmut Grasberger, Mohamad El-Zaatari, Shrinivas Bishu, Chiharu Ishii, Akiyoshi Hirayama, Kathryn A. Eaton, Belgin Dogan, Kenneth W. Simpson, Naohiro Inohara, Harry L. T. Mobley, John Y. Kao, Shinji Fukuda, Nicolas Barnich, Nobuhiko Kamada. Dietary l-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gutNature Microbiology

Read the press release from Michigan Medicine