A team of researchers from the Paris-Seine Institute of Biology (Sorbonne University/CNRS) has discovered two Drosophila genes whose products are capable of modifying RNAs. The results of their study, published in Nucleic Acids Research, characterize in detail the molecular and physiological defects observed during a loss of function of these genes in Drosophila. They could, in the future, make it possible to identify new determining biomarkers in the diagnosis of certain diseases.
Read the research paper: tRNA 2′-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila. Margarita T Angelova et al. Nucleic Acids Research