biologyevolutionresearch news

A cellular nano-machine makes a morphogenetic process irreversible

By 1st September 2019 September 10th, 2019 No Comments

There is an apparent paradox in biology: the intrinsic elasticity of tissues should counteract the mechanical forces that help organs form. What is more, permanent deformation can only be observed if there is a mechanism that blocks the cellular forms in their transient states. Researchers at the Laboratoire de biologie du développement (CNRS / Sorbonne Université / Inserm) led by Michel Labouesse have now succeeded in identifying such a mechanism and have determined the cellular micromechanics behind it. Their work is published in Nature.

Read the research paper: An actin-based viscoplastic lock ensures progressive body-axis elongation. Lardennois A, Pásti G, Ferraro T, Llense F, Mahou P, Pontabry J, Rodriguez D, Kim S, Ono S, Beaurepaire E, Gally C, Labouesse M. Nature 10.1038/s41586-019-1509-4

Read the press release from the IBPS.