lab snippets

A broad spectrum drug candidate, the PIXANO open-source tool and a speedy swimmer bacterium

By 27 février 2020 mai 31st, 2020 No Comments

Researchers from the CEA and the Institut Curie have improved the mechanism of action of a molecule capable of neutralizing the harmful effect of a large number of pathogens, including the Ebola virus, enterohemorrhagic Escherichia coli and cholera toxin. Their results, published in Nature Chemical Biology, could help in the development of a broad-spectrum drug.

© Robert Koch Institute, Germany

Source: The way is now open for the development of a broad-spectrum drug candidate for several pathogenic viruses, bacteria and toxins

In the field of artificial intelligence applied to computer vision, automatic image annotation is an essential step that conditions the quality of machine learning. Thanks to its expertise in artificial intelligence, the CEA has now developed the PIXANO tool, which effectively combines the speed of artificial systems backed up with human validation. The tool is open source and will allow the AI community – both in academia and industry – to accelerate the development of annotation solutions and technologies.

@PIXANO/CEA

Source: Lancement de l’outil open source PIXANO : l’annotation automatique d’images atteint la précision du pixel

Finally, researchers from the Biosciences and Biotechnology Institute of Aix-Marseille (BIAM, CEA/CNRS/Aix-Marseille University) in Saint-Paul lez Durance, in collaboration with researchers from the Max Planck Institute of Colloids and Interfaces in Potsdam and the University of Göttingen, have determined the trajectory and swimming speed of the magnetotactic bacterium Magnetococcus marinus, which is known to move rapidly. The speed of a 1 µm bacterium is 400-500 µm/s, making it a champion in its league. More surprisingly, the trajectory is made up of complex spirals.

Published in eLife, the exceptional properties of this bacterium means that it might be used as a micro-robot in the fields of biotechnology and the environment.

Diagram of the cell and flagella movement © K. Bente / Institut Max Planck Potsdam

Source: Magnetococcus marinus, the swimming champion bacterium